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The most com adverse interactions occurred with blood thinners such as warfarin and antiplatelet drugs such as aspirin, Qato's group found. "They are not

seeking the advice of their physician on supplement use," broad spectrum antibiotics for uti (http://community.usatourist.com/members/nerissahfranksj.aspx?t=noprescriptionneeded) she said. Among those combining drugs,
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4 percent were in danger of having
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an adverse drug reaction. 24/31 issue of the Journal of

the American Medical Association. Among commonly used medications, drug-to-drug interactions extend beyond prescription drugs, with nearly half involving the use of over-the-counter medications or dietary supplements.

Drug Combinations Putting Seniors at Risk -- As many as 4 percent of

older
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with prescription drugs in ways that put them at risk for potentially

dangerous interactions, a new survey finds. In addition, the researchers found that 68 percent of older adults
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prescription drugs plus over-the-counter medications or dietary

supplements. "Physicians and pharmacists need to ask older patients about all the
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medications cephalexin for dogs (http://wfnx.com/members/beckimhermanb.aspx?noprescriptionneeded) they use -- prescription and nonprescription -- and patients need to be prepared to share this information," Qato said.

In addition,
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almost 30 percent of seniors are taking at least five

prescription medications and many combine prescription and nonprescription drugs. Moreover, the rate of adverse drug interactions increased with age, particularly among women. Adults, about 50.5

million, used at least one medication
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regularly. "Often patients have difficulty evaluating the appropriateness of

supplements with their own medical problems," Jacobs said.

The researchers found that 91 percent of U.S. Most

medications were used by those 75 to 85 years old. Com adverse drug reactions include. Over 50
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percent
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of these interactions involved

the use of over-the-counter medications, the researchers found.

More information For more information on drug interactions, visit the U.S. National Library of Medicine .. The researchers looked for all medications, both over-the-counter and prescription, used between and March

2006. Prescription medicines
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were used by
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81 percent of adults, or 44.9 million older Americans.

In addition, almost 50 percent of older adults used at least one over-the-counter medication or dietary supplement. "No one is looking over the number of medicines they are on to look for

potential interactions,"
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Jacobs said. "If they need to self-medicate with over-the-counter drugs or dietary

supplements, they should consult with their physician or pharmacist. In addition, there has also been an increase in the use of supplements, she noted.

"There has been an intensification of therapy for disease,"

she reasoned. "The vast majority of older adults are using at least one
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and more adults are using more medications, particularly prescription medications, compared to a decade ago," said survey Qato, from the University of Chicago. More than 50 percent of those surveyed used five or more prescription drugs, over-the-counter medications or dietary supplements. However, the use of over-the-counter medications was the same for men and women, the researchers found.

Laurie Jacobs, chief of geriatric medicine at Montefiore Medical Center in New York City, believes that the potential for adverse drug reactions by mixing drugs is great and patients need to coordinate their medication use with one doctor to guard against harmful interactions. This

is particularly important in older
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people because as people get older,

they are more vulnerable to the negative effects of medications, including drug-to-drug interactions," Qato said. "And despite limited availability of drug safety information for nonprescription medications, particularly dietary supplements, they are frequently used in older adults," Qato added. Among those

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prescription medications, 29 percent used more than five drugs and

drug use increased with age among both men and women, Qato's group reports.

The report is published in the Dec. A recent report estimated that adults over 65 account for more than

175,000 emergency department visits for
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adverse drug reactions each year,

and commonly prescribed medications accounted for 33 percent of these drug reactions. Patients need to know that while medications are often beneficial, there are often risks associated with their use, Qato said. "Someone other than the patient should go over the whole list." Jacobs noted that the increase in the number of people taking drugs is a good thing. However, there has also been a growth in the number of medications and an increased effort in marketing them, which makes people seek out doctors who will prescribe them, Jacobs said. For the study, Qato's team used survey data collected on more than 3,000 adults aged 57 to 85. More women than men used prescription medications and dietary supplements.

"This is especially important in patients who see multiple providers and patients that fill at multiple pharmacies." Dr.



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